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Abstract #2397

Differential diagnosis of prostate cancer and benign prostatic hyperplasia using texture features based on multiple high b-values DWI 

Jingjun Wu1, Ailian Liu1, Jiazheng Wang2, Zhiwei Shen2, Lihua Chen1, Qingwei Song1, Renwang Pu1, and Bingbing Gao1
1Department of Radiology, the First Affiliated Hospital of Dalian Medical University, Dalian, China, 2Philips Healthcare, Beijing, China

This work aimed for multiple high b-values DWI texture features based strategy to identify prostate cancer and benign prostatic hyperplasia, which may provide more abundant and comprehensive quantitative information, and promote clinical decision-making. The results showed that the diagnostic value was improved with AUC of 0.832 (sensitivity: 0.800, specificity: 0.762) based on combined texture features from ultra-high b value (b = 800, 1200, 2000s/mm2) DWI images, which is a valuable strategy for clinical practice.

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