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Abstract #2503

Comparison of the degree of R1rho dispersion in liver between healthy volunteers and patients with liver disease

Minori Onoda1, Yu Ueda2, Satoshi Kobayashi1,3,4, Tosiaki Miyati3, Naoki Ohno3, Yudai Shogan1, Tadanori Takata1, Yukihiro Matsuura1, and Toshifumi Gabata4
1Department of Radiological Technology, Kanazawa University hospital, Kanazawa, Japan, 2Philips Japan, Tokyo, Japan, 3Faculty of Health Sciences, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan, 4Department of Radiology, Kanazawa University Hospital, Kanazawa, Japan

In this study, we compared the degree of R1rho dispersion in liver of healthy volunteers and patients with liver disease to better understand the behavior of T1rho in liver. T1rho in normal liver tissue was correlated with the perfusion-independent diffusion coefficient (D) calculated by IVIM analysis, whereas in patients with liver disease, there was no correlation between T1rho and D. Furthermore, there was no significant difference between the R1rho dispersion values in liver between volunteers and patients.

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