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Abstract #2552

Evaluating a Community-Based Diet and Lifestyle Intervention For Improved Metabolic Health in India: A Pilot Randomized Controlled Trial (RCT)

Stephen Bawden1,2, K Manoj3, Elizabeth Simpson1, K Leena4, Moira Taylor1, Sally Hibbert5, Amrita Vijay1, Laura Miller1, Jane Grove1, Ana Valdes1, Penny Gowland2, Thrivikrama Shenoy4, and Guruprasad P Aithal1
1NIHR Nottingham Biomedical Research Centre, University of Nottingham, Nottingham University Hospitals NHS Trust and the University of Nottingham, Nottingham, United Kingdom, 2Sir Peter Mansfield Imaging Centre, University of Nottingham, Nottingham, United Kingdom, 3Metro Scan and Laboratory, Trivandrum, India, 4Population Health and Research Institute, Trivandrum, India, 5Centre for Research in the Behavioural Sciences, Nottingham University Business School, Nottingham, United Kingdom

The Indian population provides important cohorts for research into metabolic disorders due to the greater prevalence of NAFLD and diabetes, and the relatively low complexity of dietary intake. In this study 71 male participants with NAFLD were recruited from a cohort in India and randomized into two groups - a 16 week low glycaemic index dietary intervention arm and a control arm. 1H MRS was used to assess liver fat fractions, alongside other metabolic markers. Results show a trend towards reduced fat fractions in the diet arm only.

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