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Abstract #2557

Metabolic imaging of brown adipose tissue with intense exercise intervention

Venkatesh Gopalan1, Kavita Kaur1, Jadegoud Yaligar1, Sanjay Kumar Verma1, Rengaraj Anantharaj1, Le Thi Thu Giang1, and S Sendhil Velan1
1Laboratory of Molecular Imaging, Singapore BioImaging Consortium,A*STAR Research Entities, Singapore, Singapore

There is a large interest in development of non-invasive methods for activation of brown adipose tissue (BAT) due to its potential to combat obesity. Exercise is a non-pharmacological strategy to combat obesity by increasing EE. In this study we have investigated exercise induced BAT activation, heat and RER in sedentary and exercise groups. Our results show that exercise activates the brown fat with reduction in fat fraction, increased heat and RER. UCP1 expression shows that reduction in “white” like adipocytes in exercise group.

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