Meeting Banner
Abstract #2558

Estimation of the triglyceride fatty acid composition in human adipose tissue using multi-TE and SHORTIE STEAM: in vitro validation using GC-MS

Stefan Ruschke1, Dominik Weidlich1, Julius Honecker 2, Claudine Seeliger2, Josef Ecker3, Olga Prokopchuk4, Hans Hauner2, and Dimitrios C Karampinos1
1Department of Diagnostic and Interventional Radiology, School of Medicine, Technical University of Munich, Munich, Germany, 2Else Kröner Fresenius Center for Nutritional Medicine, Technical University of Munich, Freising, Germany, 3ZIEL Institute for Food & Health, Research Group Lipid Metabolism, Technical University of Munich, Freising, Germany, 4Department of Surgery, Klinikum rechts der Isar, School of Medicine, Technical University of Munich, Munich, Germany

There is a growing interest in utilizing single-voxel $$$^1$$$H MR spectroscopy (MRS) for probing the triglyceride fatty acid composition by means of the number of double bounds (ndb) and number of methylene interrupted double bounds (nmidb) per triglyceride as well as the mean fatty acid carbon chain length (CL). The present study investigates the in vitro measurement agreement of fatty acid composition parameters between single-voxel multi-TE and short-TR multi-TI multi-TE (SHORTIE) STEAM spectroscopy and the gold standard gas chromatography-mass spectrometry (GC-MS) in human subcutaneous and visceral adipose tissue samples.

This abstract and the presentation materials are available to 2020 meeting attendees and eLibrary customers only; a login is required.

Join Here