This study evaluates apparent diffusion coefficient (ADC)
as measured by a quantitative double echo steady state (qDESS) sequence as a
biomarker for early osteoarthritis detection in articular cartilage in the femur
and its correlation with ADC from a diffusion weighted echo planar (DWI-EPI) scan. 9 injured knees and contralateral knees of patients
undergoing reconstruction surgery following anterior cruciate ligament tears
were scanned with qDESS and DWI-EPI sequences up to 18 months post surgery.
There were no consistent patterns of qDESS ADC change on a global or
regional basis in the femoral cartilage.
qDESS ADC did not correlate with DWI-EPI ADC.