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Abstract #2838

Osteochondral Junction Imaging Using Adiabatic Inversion Recovery Prepared Fat-Saturated Zero Echo Time MR Imaging: A Feasibility Study

Hyungseok Jang1, Yajun Ma1, Michael Carl2, Saeed Jerban1, Eric Chang1,3, and Jiang Du1
1University of California, San Diego, San Diego, CA, United States, 2GE Healthcare, La Jolla, CA, United States, 3VA San Diego Healthcare System, San Diego, CA, United States

Cartilage has a complex structure comprised of multiple zones with different MR signal properties. Among them, osteochondral junction (OCJ) cannot be directly imaged with conventional MR imaging techniques. In this study, we explore the feasibility of inversion recovery prepared fat-saturated zero echo time (IR-FS-ZTE) to image the human knee OCJ. To accentuate the signal from the OCJ region with short T2*, adiabatic inversion recovery along with fat-saturation preparation was applied, followed by continous, slient ZTE imaging. The feasibility and efficacy of IR-FS-ZTE were shown in ex vivo cadaveric human knee joints and in in vivo healthy volunteers.

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