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Abstract #2871

Osprey: Open-Source Processing, Reconstruction & Estimation of Magnetic Resonance Spectroscopy Data

Georg Oeltzschner1,2, Helge Jörn Zöllner1,2, and Richard Anthony Edward Edden1,2
1Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD, United States, 2F. M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, MD, United States

Magnetic resonance spectroscopy (MRS) offers a wide range of methods to study in vivo metabolism. As a result of this diversity, data acquisition and analysis are far from standardized, and researchers frequently develop customized and therefore highly heterogeneous pipelines, often interfacing with commercial or closed-source external fitting software. Here, we present “Osprey”, an all-in-one software package that incorporates all steps of state-of-the-art pre-processing, linear-combination modeling, tissue correction, quantification, and visualization of MRS data from the human brain. Osprey provides a modular, fully open-source framework, allowing the community to rapidly incorporate future methodological developments, accelerate their adaptation, and foster standardization.

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