Abstract #2898

Dual-voxel 1H MR spectroscopy in mouse brain at 14.1T with dynamic shim update (DSU) acquisition scheme

Hikari Yoshihara¹, Nicolas Kunz², Jean-Claude Martinou³, and Hongxia Lei²

¹Laboratory for Metabolic Imaging, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland, ²Animal Imaging and Technology Core (AIT), Center for Biomedical Imaging (CIBM), Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland, ³Faculty of Science, University of Geneva, Geneva, Switzerland

Dynamic shimming updates with first- and second-order shims are essential for dual-voxel spectroscopy of mouse cortex and hippocampus at high magnetic field. We show that DSU is feasible for studying pharmacological effects in transgenic mice at 14.1 T.

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