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Abstract #2898

Dual-voxel 1H MR spectroscopy in mouse brain at 14.1T with dynamic shim update (DSU) acquisition scheme

Hikari Yoshihara1, Nicolas Kunz2, Jean-Claude Martinou3, and Hongxia Lei2
1Laboratory for Metabolic Imaging, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland, 2Animal Imaging and Technology Core (AIT), Center for Biomedical Imaging (CIBM), Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland, 3Faculty of Science, University of Geneva, Geneva, Switzerland

Dynamic shimming updates with first- and second-order shims are essential for dual-voxel spectroscopy of mouse cortex and hippocampus at high magnetic field. We show that DSU is feasible for studying pharmacological effects in transgenic mice at 14.1 T.

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