Meeting Banner
Abstract #2913

Rapid acquisition of semi-LASER MR spectroscopic imaging using symmetric EPSI encoding: A preliminary study in phantom and human brain

Sunitha Thakur1, Olivia Sutton1, Eduardo Coello2, Alexander Lin2, Ralph Noeske3, Ricardo Otazo1, and Robert Young1
1Memorial Sloan Kettering Cancer Center, New York, NY, United States, 2Brigham and Women’s Hospital, Boston, MA, United States, 3MR Applied Science Lab, GE Healthcare, Berlin, Germany

The aim of this study was to develop and test rapid MR spectroscopic imaging (MRSI) in patients with brain tumors. We implemented and optimized rapid MRSI at 3T using semi-localization by adiabatic selective refocusing pulses (semi-LASER), fast spatial encoding using symmetric echo planar spectroscopic imaging (EPSI), and robust water suppression with variable power and optimized relaxation delays. This rapid imaging approach was tested in a phantom and subsequently in a volunteer and a patient. In vivo studies demonstrated that high quality MRSI data with voxel volumes less than 0.5 mL can be collected within a clinically feasible time (2 minutes).

This abstract and the presentation materials are available to 2020 meeting attendees and eLibrary customers only; a login is required.

Join Here