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Abstract #2960

Metabolic profiles of blood plasma in prostate cancer patients having different dietary patterns

Pradeep Kumar1, Rajeev Kumar 2, Sanjay Sharma3, Sanjay Thulkar4, S. Datta Gupta5, S. senthil Kumaran1, Rama Jayasundar1, N. R. Jagannathan6, and Virendra Kumar1
1Department of NMR, All India Institute of Medical Sciences, New Delhi, India, Ansari nagar, India, 2Department of Urology, All India Institute of Medical Sciences, New Delhi, India, Ansari nagar, India, 3Department of Radio-diagnosis, RPC, All India Institute of Medical Sciences, New Delhi, India, Ansari nagar, India, 4Department of Radio-diagnosis, IRCH, All India Institute of Medical Sciences, New Delhi, India, Ansari nagar, India, 5Department of Pathology, All India Institute of Medical Sciences, New Delhi, India, Ansari nagar, India, 6Present address: Department of Radiology, Chettinad Academy of Research and Education, Kelambakkam, Tamil Nadu, India

In the present study we reported the effect of dietary lifestyle on metabolic profile of blood plasma in prostate cancer (PCa) patients using NMR spectroscopy the long term effects of dietary patterns our metabolic profiles and PCa have been reported in literatures. A significantly higher concentration of choline, glutamate, creatine, succinate, 1-methylhistidine and methionine were observed in non-vegetarians patients compared to vegetarians. Our results suggested that the metabolic pathway alterations seen in amino acids, phospholipids and energy may be related to changes due diet to and PCa progression.

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