Abstract #2960

Metabolic profiles of blood plasma in prostate cancer patients having different dietary patterns

Pradeep Kumar¹, Rajeev Kumar ², Sanjay Sharma³, Sanjay Thulkar⁴, S. Datta Gupta⁵, S. senthil Kumaran¹, Rama Jayasundar¹, N. R. Jagannathan⁶, and Virendra Kumar¹

¹Department of NMR, All India Institute of Medical Sciences, New Delhi, India, Ansari nagar, India, ²Department of Urology, All India Institute of Medical Sciences, New Delhi, India, Ansari nagar, India, ³Department of Radio-diagnosis, RPC, All India Institute of Medical Sciences, New Delhi, India, Ansari nagar, India, ⁴Department of Radio-diagnosis, IRCH, All India Institute of Medical Sciences, New Delhi, India, Ansari nagar, India, ⁵Department of Pathology, All India Institute of Medical Sciences, New Delhi, India, Ansari nagar, India, ⁶Present address: Department of Radiology, Chettinad Academy of Research and Education, Kelambakkam, Tamil Nadu, India

In the present study we reported the effect of dietary lifestyle on metabolic profile of blood plasma in prostate cancer (PCa) patients using NMR spectroscopy the long term effects of dietary patterns our metabolic profiles and PCa have been reported in literatures. A significantly higher concentration of choline, glutamate, creatine, succinate, 1-methylhistidine and methionine were observed in non-vegetarians patients compared to vegetarians. Our results suggested that the metabolic pathway alterations seen in amino acids, phospholipids and energy may be related to changes due diet to and PCa progression.

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