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Abstract #2978

Sodium TQ signal cancelation due to B0 inhomogeneities despite the use of a refocusing pulse

Dennis Kleimaier1 and Lothar R. Schad1
1Computer Assisted Clinical Medicine, Heidelberg University, Mannheim, Germany

The sodium TQ signal is sensitive to B0 inhomogeneities leading to TQ signal cancelation. In this study, we evaluated three different shim routines to assess the robustness to B0 inhomogeneities and the reproducibility of the sodium TQ signal. Using an optimized shim routine, the TQ signal dependence on potassium concentration was investigated. Severe B0 inhomogeneities caused a reduction in the TQ signal, despite using a refocusing pulse, without affecting the transversal relaxation times. To achieve reproducible TQ measurements, the FWHM of the sodium SQ signal must be specified. Addition of different amounts KCl caused a reduction in the TQ signal.

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