Abstract #2993

tcaCALC: MATLAB Software for Quantitative Analysis of 13C Metabolic Isotopic Tracer Experiments

Jeffry R. Alger^1,2,3, Gaurav Sharma¹, A. Dean Sherry^1,4, and Craig R. Malloy^1,5

¹Advanced Imaging Research Center, University of Texas, Southwestern Medical Center, Dallas, TX, United States, ²Neurology, University of California, Los Angeles, Los Angeles, CA, United States, ³NeuroSpectroScopics LLC, Sherman Oaks, CA, United States, ⁴Department of Chemistry, Universiy of Texas at Dallas, Richardson, TX, United States, ⁵Department of Internal Medicine, University of Texas-Southwestern Medical Center, Dallas, TX, United States

tcaCALC has been developed as a MATLAB tool that facilitates the quantitative analysis of metabolic tracing experiments that use ¹³C enriched tracers. The most recent version of tcaCALC facilitates analysis by incorporating spectral fitting of J-coupled ¹³C NMR multiplets and modeling complex metabolic situations in which specific metabolic fluxes may be active or inactive. The MATLAB source code and a compiled version are available for sharing to interested research teams.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.