Meeting Banner
Abstract #3006

Investigating cardiac metabolism between the fasted and fed state using hyperpolarized [1-13C]pyruvate MRI

Shuyu Tang1, Jing Liu1, Robert Bok1, Karen Ordovas1, Jeremy Gordon1, James Slater1, M. Roselle Abraham1, and Peder Larson1
1University of California, San Francisco, San Francisco, CA, United States

In this work, we investigated the influence of a fed versus fasted state on human heart metabolism using hyperpolarized [1-13C]pyruvate MRI in order to develop protocols for human studies of heart disease. Good image quality was obtained in all volunteers, and approximately 40-50% increases in the lactate and bicarbonate signals were observed in the fed state. Distinct metabolic patterns are observed between the left and right ventricle and warrant further investigation.

This abstract and the presentation materials are available to members only; a login is required.

Join Here