Abstract #3026

Rapid Multi-Point B1+ Calibration for Large Field-of-View 13C Imaging

Nadia D. Bragagnolo^1,2, Benjamin J. Geraghty^1,2, Casey Y. Lee^1,2, Albert P. Chen³, and Charles H. Cunningham^1,2

¹Medical Biophysics, University of Toronto, Toronto, ON, Canada, ²Physical Sciences, Sunnybrook Research Institute, Toronto, ON, Canada, ³GE Healthcare Technologies, Toronto, ON, Canada

This project aims to minimize the B₁⁺ field inhomogeneities that arise when using a flexible transmit coil system in multi-organ hyperpolarized ¹³C MRI. A method for rapid B₁⁺ measurement of several locations immediately prior to image acquisition was developed to determine scaling factors for the power input of slices over a large field-of-view. These scaling factors ensure that the desired flip angle is achieved across multiple organs. The rapid B₁⁺ measurement technique has been tested in in vivo scans, giving values accurate within ±1μT. This method will be used to minimize the variability in multi-organ thoracic and abdominal imaging.

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