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Abstract #3026

Rapid Multi-Point B1+ Calibration for Large Field-of-View 13C Imaging

Nadia D. Bragagnolo1,2, Benjamin J. Geraghty1,2, Casey Y. Lee1,2, Albert P. Chen3, and Charles H. Cunningham1,2
1Medical Biophysics, University of Toronto, Toronto, ON, Canada, 2Physical Sciences, Sunnybrook Research Institute, Toronto, ON, Canada, 3GE Healthcare Technologies, Toronto, ON, Canada

This project aims to minimize the B1+ field inhomogeneities that arise when using a flexible transmit coil system in multi-organ hyperpolarized 13C MRI. A method for rapid B1+ measurement of several locations immediately prior to image acquisition was developed to determine scaling factors for the power input of slices over a large field-of-view. These scaling factors ensure that the desired flip angle is achieved across multiple organs. The rapid B1+ measurement technique has been tested in in vivo scans, giving values accurate within ±1μT. This method will be used to minimize the variability in multi-organ thoracic and abdominal imaging.

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