Abstract #3038

Towards Comprehensive Assessment of Lung Injury Using Multi-Modality Hyperpolarized MRI

Mehrdad Pourfathi¹, Hooman Hamedani^1,2, Yi Xin^1,2, Stephen J Kadlecek¹, Ian Duncan¹, Maurizio Cereda^1,3, Sarmad Siddiqui¹, Harrilla Profka¹, Luis Loza¹, Faraz Amzajerdian ^1,2, Tahmina Achekzai¹, Kai Ruppert¹, Michael Rosalino¹, Federico Sertic^1,4, Ryan Baron¹, Jon Snow¹, Yiwen Qian^1,2, Gabriel Unger¹, Shampa Chatterjee⁵, and Rahim R. Rizi¹

¹Radiology, University of Pennsylvania, Philadelphia, PA, United States, ²Bioengineering, University of Pennsylvania, Philadelphia, PA, United States, ³Anesthesiology and Critical Care, University of Pennsylvania, Philadelphia, PA, United States, ⁴Surgery, University of Pennsylvania, Philadelphia, PA, United States, ⁵Physiology, University of Pennsylvania, Philadelphia, PA, United States

Hyperpolarized ¹³C and ¹²⁹Xe MRI are novel imaging methods that have been used to characterize tissue metabolism and lung function, respectively. In this study, we demonstrate the use of these techniques in tandem in order to characterize lung injury in a porcine model of aspiration pneumonitis.

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