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Abstract #3063

Magnetic Resonance Imaging of Single-Cell Dynamics in the Olfactory Bulb

Nikorn Pothayee1, Stephen Dodd1, Gary Zabow2, and Alan Koretsky1
1Laboratory of Functional and Molecular Imaging, National Institutes of Health, Bethesda, MD, United States, 2Magnetic Imaging Group, National Institute of Standards and Technology, Boulder, CO, United States

There is great potential if single cells can be tracked in vivo in the mammalian brain. Here, we demonstrate the applicability of microfabricated gold-coated iron particles for in vivo tracking of single-cell dynamics. These particles have a pure iron core as opposed to the more commonly used iron-oxide based particles. Following in situ labeling of neural precursor cells, we show that the migration of individual cells can be visualized in real-time.

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