Abstract #3089

Real-time motion and retrospective receiver sensitivity correction for gluCEST using volumetric navigators (vNavs) at 7T

Esau Poblador Rodriguez¹, Philipp Moser¹, Sami Auno², Korvinian Eckstein¹, Stephan Gruber¹, Benjamin Schmitt³, Andre van de Kouwe⁴, Siegfried Trattnig ¹, and Wolfgang Bogner¹

¹High Field MR Centre, Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria, ²Department of Physics, University of Helsinky, Helsinki, Finland, ³Siemens Healthineers, Sydney, Australia, ⁴Harvard Medical School, Boston, MA, United States

CEST is susceptible to subject motion not only due to misregistration of MR images acquired over time and subsequent alterations of B0 field, but also due to the related receiver sensitivity (B1-) inhomogeneities. We propose to correct for ∆B1- from the images generated by an interleaved EPI navigator used for prospective motion correction. We show the benefit of the proposed method, in combination with B1+ and dynamic B0 corrections, to restore a glutamate weighted CEST map in an active healthy volunteer.

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