CEST MRI exploits saturation transfer-induced proton exchange and its corresponding, indirect loss of water signal, has been shown to provide a novel contrast mechanism in MRI. However, CEST MRI is prone to B0 inhomogeneities. To resolve this problem, CEST MRI requires multiple-acquisition. To acquire z-spectrum of whole brain at ultrahigh field of 7T, there are multiple issues to be tackled; a prohibitively long acquisition time, potential high power deposition, and B0 drift during a long scanning time. In this work, we proposed the rapid steady-state CEST MRI pulse sequence incorporating with incoherent sampling in 3D segmented EPI at 7T
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