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Abstract #3126

Fast 2D EPI multislice imaging for full APT-CEST brain coverage

Jan-Rüdiger Schüre1, Manoj Shrestha2, Eike Steidl3, Ralf Deichmann2, Elke Hattingen3, Marlies Wagner3, and Ulrich Pilatus3
1Neuroradiology, Goethe University Hospital, Frankfurt am Main, Germany, 2Brain Imaging Center (BIC), Frankfurt am Main, Germany, 3Goethe University Hospital, Frankfurt am Main, Germany

We present a fast 2D EPI multislice sequence that allows to acquire the APT-CEST contrast in 16 slices within 8 seconds. The fast CEST-EPI sequence was compared in vitro and in vivo with a steady-state CEST sequence, where the saturation is applied for 4 s for each frequency offset. The reduced acquisition time in the fast sequence can be used for measurement repetitions or additional MR examinations (e.g. MR spectroscopic imaging).

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