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Abstract #3174

R1 reproducibility at 3T and 7T using Bloch-Siegert based corrections for transmit field inhomogeneity

Nadège Corbin1 and Martina F Callaghan1
1Wellcome Centre for Human Neuroimaging, UCL Institute of Neurology, London, United Kingdom

High reproducibility of longitudinal relaxation rate (R1) estimation using the variable flip angle approach requires unbiased and precise estimation of the transmit field inhomogeneity. In this context, the Bloch-Siegert (BSS)-based B1+ mapping approaches were evaluated at 3T and 7T and compared to the SE/STE approach. R1 values in grey and white matter were slightly higher with the BSS-based techniques. At 3T, the highest reproducibility was observed with the single-echo BSS approach, using an RF spoiling increment of 90°. At 7T, the reproducibility of the techniques were equivalent in well B0-shimmed regions but diverged in regions of high B0 inhomogenity.

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