Microbubbles are a well-established intravascular ultrasound contrast agent. There is increasing interest in MRI-guided microbubble-mediated focused ultrasound treatments such as thermal surgery. MRI magnitude has a non-linear and non-local dependence on microbubble size and volume fraction, making it unsuitable for estimating microbubble concentrations. Quantitative Susceptibility Mapping (QSM) is a strong candidate for tracking microbubble concentration, destruction and clearance because the susceptibility depends linearly on the volumetric bubble concentration. Here, we show the first QSM of microbubbles in a phantom and observe that the measured susceptibility has a high SNR and is directly proportional to the microbubble volumetric concentration.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords