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Abstract #3263

Use of arterial spin labeling MRI in differentiating fat-poor angiomyolipoma from clear cell renal cell carcinoma

Qing Xu1, Weiqiang Dou2, and Jing Ye1
1Department of Radiology, Clinical Medical School of Yangzhou University, Northern Jiangsu People’s Hospital, Yangzhou, 457, China, 2GE Healthcare, MR Research China, Beijing, China

In this study, we aimed to test if arterial spin labeling (ASL) MRI can be used to differentiate renal fat-poor angiomyolipoma (AML) from the clear cell renal cell carcinoma (ccRCC). To achieve this goal, we compared the ASL derived parameters including tumor blood flow (TBF), tumor-to-cortex ratio, and tumor-to-medulla ratio between fat-poor AML and ccRCC. Our results showed that TBF, tumor-to-cortex and tumor-to-medulla ratios were notably higher in ccRCC group than in fat-poor AML group (270.49±78.88ml/100g/min vs. 146.68±47.21ml/100g/min, 1.22±0.26 vs. 0.74±0.14, 3.13±0.94 vs. 1.77±0.55; p<0.05), indicating that ASL MRI can be an effective tool in differentiating fat-poor AML from ccRCC.

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