Pathophysiological changes in cerebrovascular reactivity can remain undetectable at rest, and may only become apparent during a cerebrovascular challenge. We evaluated the feasibility of dynamically measuring the cerebrovascular response to exercise using pseudo-continuous arterial spin labeling (pCASL) at 3 Tesla during a bicycle exercise-recovery stress test. We observed a transient increase in cerebrovascular blood flow (CBF) during exercise in four volunteers, demonstrating that pCASL-MRI can capture dynamic changes in CBF during physiological bicycle exercise. This approach may become an important quantitative tool to noninvasively investigate the cerebrovascular reactivity in health and disease.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords