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Abstract #3277

Robust non-contrast pulmonary perfusion imaging using pseudo-continuous arterial spin labeling with background suppression

Joshua S. Greer1,2, Yiming Wang2, Limin Zhou2, Tarique Hussain1,2, and Ananth J. Madhuranthakam2,3
1Pediatrics, UT Southwestern Medical Center, Dallas, TX, United States, 2Radiology, UT Southwestern Medical Center, Dallas, TX, United States, 3Advanced Imaging Research Center, UT Southwestern Medical Center, Dallas, TX, United States

Pulmonary perfusion imaging using ASL has been demonstrated using the pCASL technique with varying degrees of reproducibility. In this study, a pCASL labeling strategy is proposed to improve the stability of perfusion signal in the lungs using cardiac triggering to reduce flow-induced signal variations, and background suppression to improve SNR. With the proposed technique, high SNR perfusion images are created with a limited number of signal averages. This optimized approach may allow full coverage of the lungs in clinically reasonable scan times.

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