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Abstract #3284

Mitigating spurious transit time artifacts in background-suppressed multi-delay 3D pseudo-continuous ASL using inflow suppression

Tianye Lin1,2, Jianxun Qu2, and John A. Detre2
1Chinese Academy of Medical Sciences, Peking Union Medical College, PUMCH, Beijing, China, 2University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, United States

The purpose of our study was to demonstrate that the inflow of arterial blood in post-labeling delay can cause intravascular high signal in multi-PLD ASL that resembles arterial transit artifact and potentially interfere with clinical interpretation. An optimized inflow-saturation method was used to suppress this artifact and improve the image quality of Hadamard-encoded and sequential multi-PLD ASL.

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