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Abstract #3285

Separating spin-compartment in arterial spin labeling using delays alternating with nutation for tailored excitation (DANTE) pulse

Shota Ishida1, Hirohiko Kimura2, Naoyuki Takei3, Yasuhiro Fujiwara4, Tsuyoshi Matsuda5, Yuki Matta1, Masayuki Kanamoto1, Nobuyuki Kosaka2, and Eiji Kidoya1
1Radiological center, University of Fukui Hospital, Eiheiji, Japan, 2Department of Radiology, Faculty of Medical Sciences, University of Fukui, Eiheiji, Japan, 3Global MR Applications and Workflow, GE Healthcare Japan, Hino, Japan, 4Department of Medical Image Sciences, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan, 5Division of Ultra-high Field MRI, Institute for Biomedical Science, Iwate Medical University, Shiwa-gun, Japan

Delays alternating with nutation for tailored excitation (DANTE) pulse is capable of uniform and flow velocity related signal suppression. DANTE-ASL was compared to T2-mesurement in ASL (T2-ASL) to validate what spin-compartment is suppressed by DANTE. T2-ASL showed labeled signal remained in vascular compartment even at a PLD of 2.0 s. However, ASL signals using DANTE were approximately similar value in all the PLDs (0.5, 1.0, 2.0, and 3.0 s), because ASL signals in vascular compartment were suppressed selectively and sufficiently with concurrently preserving signals in tissue compartment. We could eliminate vascular compartment from total ASL signal using DANTE.

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