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Abstract #3782

Increasing robustness to fat partial volume effects in T1-mapping with MOLLI

Andreia S Gaspar 1, Andreia C Freitas1, and Rita G Nunes1
1ISR-Lisboa/LARSyS and Department of Bioengineering, Instituto Superior Técnico – Universidade de Lisboa, Lisbon, Portugal

Modified Look-Locker inversion recovery (MOLLI) with a balance Steady State Free Precession (bSSFP) readout is widely applied in the clinical setting but it is known to be sensitive to fat partial volume effects (PVE), as well as static B0 field inhomogeneities (ΔB0). As an alternative, the FLASH readout, more robust to ΔB0, can be applied for T1 mapping. In this work we studied the robustness of FLASH-MOLLI to fat PVE, and propose a new bi-component model to improve the accuracy of water T1 estimates in both bSSFP and FLASH MOLLI.

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