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Abstract #3789

Estimation of net receive sensitivity - at 3T and 7T - for correction of inter-scan motion artefacts in R1 mapping

Yaël Balbastre1, Nadège Corbin1, and Martina F Callaghan1
1Wellcome Centre for Human Neuroimaging, University College London, London, United Kingdom

The longitudinal relaxation rate is a useful myelin proxy that can be estimated by combining multiple acquisitions with different nominal flip angles. Inter-scan motion can introduce large biases that can be efficiently corrected if reference data with a relatively ‘flat’ sensitivity profile, e.g. a body coil, is available. This is generally not the case at ultra-high field where highly inhomogeneous localised transmit-receive coils are used. Therefore, we propose a new method for estimating and removing the net coil sensitivity that does not require a body coil, needs only coil-wise magnitude images, yet reduces motion-induced bias in R1.

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