Abstract #3793

Variable flip angle T1 mapping with MT-balanced RF pulses

Nam Gyun Lee¹, Zhibo Zhu², and Krishna S. Nayak²

¹Biomedical Engineering, University of Southern California, Los Angeles, CA, United States, ²Electrical and Computer Engineering, University of Southern California, Los Angeles, CA, United States

Quantitative DCE requires accurate and precise pre-contrast M₀/T₁ maps. Variable flip angle (VFA) T1 mapping has good precision but has accuracy issues. Magnetization transfer (MT) effects is one of the major reasons for differences between VFA and reference IR-FSE T1 measurements. Here, we apply the recent framework for MT-balanced RF pulse design to high-resolution whole-brain T1 mapping.

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