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Abstract #3793

Variable flip angle T1 mapping with MT-balanced RF pulses

Nam Gyun Lee1, Zhibo Zhu2, and Krishna S. Nayak2
1Biomedical Engineering, University of Southern California, Los Angeles, CA, United States, 2Electrical and Computer Engineering, University of Southern California, Los Angeles, CA, United States

Quantitative DCE requires accurate and precise pre-contrast M0/T1 maps. Variable flip angle (VFA) T1 mapping has good precision but has accuracy issues. Magnetization transfer (MT) effects is one of the major reasons for differences between VFA and reference IR-FSE T1 measurements. Here, we apply the recent framework for MT-balanced RF pulse design to high-resolution whole-brain T1 mapping.

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