Abstract #3818

Mouse fMRI of visual stimulation in awake vs. anesthetized condition

THI NGOC ANH DINH¹ and Seong Gi Kim¹

¹Department of Biomedical Engineering, Sungkyunkwan University, Center for Neuroscience Imaging Research, Institute for Basic Science (IBS), Suwon-si, Korea, Republic of

Mouse fMRI has been increasingly used in the MRI community. Here, we developed an awake mouse fMRI protocol and compared BOLD fMRI responses responding to visual stimulation of 5 Hz and 10 Hz, obtained during awake and anesthetized conditions. Our 9.4-T BOLD-fMRI showed activities in all visual areas including LGN, superior colliculus, and V1, and can be well-explained by electrophysiology literature.

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