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Abstract #3818

Mouse fMRI of visual stimulation in awake vs. anesthetized condition

THI NGOC ANH DINH1 and Seong Gi Kim1
1Department of Biomedical Engineering, Sungkyunkwan University, Center for Neuroscience Imaging Research, Institute for Basic Science (IBS), Suwon-si, Korea, Republic of

Mouse fMRI has been increasingly used in the MRI community. Here, we developed an awake mouse fMRI protocol and compared BOLD fMRI responses responding to visual stimulation of 5 Hz and 10 Hz, obtained during awake and anesthetized conditions. Our 9.4-T BOLD-fMRI showed activities in all visual areas including LGN, superior colliculus, and V1, and can be well-explained by electrophysiology literature.

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