A novel method for simultaneous functional and anatomical imaging is presented for high-resolution fMRI at 7T. An RF inversion pulse is used before two EPI acquisition trains where functional scans are acquired alternating between shorter and longer inversion times (TIs). Post-processing division of the shorter TI functional scan with the longer TI functional scan allows improved localization of brain activity in high-resolution fMRI at 7T. The proposed method allows simultaneous imaging of brain function and anatomy as the grey matter tissues can easily be segmented out from the resulting functional images, ensuring their perfect alignment required for detecting functional activity.
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