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Abstract #3821

In vivo Direct MR Imaging of Mouse Whisker Sensory Responses

Tan Toi Phan1,2 and Jang-Yeon Park1,2
1Department of Biomedical Engineering, Sungkyunkwan University, Suwon, Republic of Korea, 2Center for Neuroscience Imaging Research, Institute for Basic Science, Suwon, Republic of Korea

Although there are debates on direct MR imaging of neuronal activity, the feasibility of this topic has been finding in various different ways. Herein, we propose an effective method of line-scan-based FLASH (LS-FLASH) imaging to directly capture sensory responses of in vivo mouse brain with a 5-ms temporal resolution. The response delay of ~10 - 15 ms between the thalamus and somatosensory barrel cortex (S1BF) was observed when the electrical stimulation was applied to the left mouse whisker area.

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