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Abstract #3854

Region-to-region covariation of cerebral blood flow in the young brain before and after acute exercise

Nicholas J. Luciw1,2, Benjamin I. Goldstein2,3, and Bradley J. MacIntosh1,2
1Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada, 2Sunnybrook Research Institute, Toronto, ON, Canada, 3Departments of Psychiatry and Pharmacology, University of Toronto, Toronto, ON, Canada

Functional brain networks reflect inherent inter-regional relationships that subserve behaviour and information processing. There is evidence that the correlations of regional brain function across individuals partly reflect functional connectivity. The current study focuses on region-to-region covariation of cerebral blood flow (CBF) across participants using arterial spin-labelled MRI. To investigate the stability of this CBF covariance mapping, we compare maps acquired within the same day but before and after a single exercise session. To refine our CBF covariance mapping methodology, we consider whether choice of anatomical atlas and use of partial volume correction impact the results of our between-session comparison.

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