Abstract #3855

Assessment of longitudinal cerebrovascular reactivity measurements based on breath-hold and resting state BOLD multi-echo fMRI

Stefano Moia¹, Rachael C. Stickland², Maite Termenon¹, Eneko Uruñuela-Tremiño¹, César Caballero-Gaudes¹, and Molly G. Bright^2,3

¹Basque Center on Cognition Brain and Language, San Sebastián, Spain, ²Physical Therapy and Human Movement Sciences, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States, ³Biomedical Engineering, McCormick School of Engineering, Northwestern University, Evanston, IL, United States

Cerebrovascular reactivity (CVR) is an important measure of vascular function, but true variability in CVR can be masked by numerous confounds. We explore the variability of CVR maps, extracted using breath-holding and resting state data, over 9 weekly scanning sessions. Our results show that CVR demonstrates robust spatial patterns that vary across known neural networks.

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