Abstract #3897

Use of functional correlation tensors for correlating white matter fMRI and brain structure

Tory Frizzell^1,2, Lukas Algis Grajauskas^2,3, Careesa Chang Liu^1,2, Sujoy Ghosh Hajra^1,2, Xiaowei Song^2,4, and Ryan C.N. D'Arcy^2,5,6

¹Engineering Science, Simon Fraser University, Burnaby, BC, Canada, ²SFU ImageTech Lab, Health Science and Innovation, Surrey Memorial Hospital, Fraser Health, Surrey, BC, Canada, ³Cummings School of Medicine, University of Calgary, Calgary, AB, Canada, ⁴Biomedical Physiology and Kinesiology, Simon Fraser University, Burnaby, BC, Canada, ⁵Faculty of Applied Science, Simon Fraser University, Burnaby, BC, Canada, ⁶Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, BC, Canada

White matter functional activity is a neglected area of research and key component for understanding the brain’s ability to adapt and learn. Participants completed a fine motor task during functional scans. DTI images were also collected for structural comparison. Functional correlation tensors were computed to examine local functional signal synchronicity. Strong agreement was found between the functional anisotropy maps and the structural anisotropy maps. Functional correlation tensors substantiate white matter functional response and identify a novel link between structure and function.

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