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Abstract #4112

An efficient approach for simultaneous PRF-T1 MR thermometry and shear wave elastography to monitor MR-guided focused ultrasound therapies

Henrik Odéen1, Lorne Hofstetter1, and Dennis L Parker1
1Radiology and Imaging Sciences, University of Utah, Salt Lake City, UT, United States

Treatment endpoint assessment in MRgFUS is commonly performed by investigating non-perfused volume or accumulated thermal dose, but these measurements can be inaccurate and have low precision immediately after treatment and can be tissue type dependent. In this work we present a pulse sequence which can provide dynamic measurements of PRF thermometry (and hence also thermal dose), T1 and tissue mechanical properties through shear wave speed measurements. PRF and T1 can provide complete MR thermometry in all tissue types (aqueous and adipose), and together all parameters are useful in treatment endpoint assessment.

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