We aimed to monitor the focused ultrasound (FUS)-induced stable cavitation (SC) by using single-shot turbo spin-echo based sequence in in vivo experiments. The FUS were transmitted to the cortex ~2‐mm beneath the superior sagittal sinus of rats with acoustic pressure=0.5 or 0.8 MPa. A cavitation index map was computed to highlight the occurrence of SC at focus. In conclusion, the simultaneous acquisitions of spin-echo based images during FUS transmission and the proposed CI map can immediately localize the position occurring SC. The relevant information can be feedbacked to FUS facility for improving the procedure of BBB opening.