An practical MR thermometry technique for fat-water mixed tissues was proposed. Fatty tissue temperature was quantified by T2 synthesized from T2’s of methylene chain and terminal methyl obtained by chemical shift suppression of water and surrounding fatty acid components. While the aqueous tissue temperature was estimated by PRF shift of water proton. Those maps were then integrated into one based on the fat and water contents in each voxel. The resultant in vitro images demonstrated the usefulness of the technique.