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Abstract #4429

Indetermination-free cytoarchitecture measurements in brain gray matter via a forward diffusion MRI signal separation method

Maëliss Jallais1 and Demian Wassermann1
1Université Paris-Saclay, Inria, CEA, Palaiseau, France

Non-invasive imaging at the cellular level could lead us to quantify grey matter tissue cytoarchitecture, which has so far been accessible only through histology, or by indeterminate-prone approaches.

We propose a new dMRI-based index to study modulated by the size of the somas. This index can be extracted without indeterminations from any acquisition including three b-values superior to 3 ms/μm2. Simulations were experimentally confirmed by tests on the HCP MGH data set.

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