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Abstract #4431

Varying the frequency-content of high b-value spherical diffusion encoding improves the characterisation of isotropic restricted compartment

Malwina Molendowska1, Mark Drakesmith1, Derek K. Jones1, and Chantal M. W. Tax1
1Cardiff University Brain Research Imaging Centre (CUBRIC), Cardiff University, Cardiff, United Kingdom

The use of ultra-strong diffusion gradient systems facilitates high b-values to suppress the signal from biological compartments with significant mobility, and as such the complexity of the model fit can be reduced. Here, we adopt isotropic encoding at high b-values to isolate spherical restricted compartments, and explore whether adding waveforms with different frequency-characteristics give an improvement in parameter-estimation of the spherical compartment.

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