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Abstract #4486

Advantage of readout-segmented EPI in simultaneous multi-slice diffusion MRI measurements for identifying uncinate fasciculus

Hiromasa Takemura1,2, Wei Liu3, Hideto Kuribayashi4, and Ikuhiro Kida1,2
1Center for Information and Neural Networks, National Institute of Information and Communications Technology, Suita, Japan, 2Graduate School of Frontier Biosciences, Osaka University, Suita, Japan, 3Siemens Shenzhen Magnetic Resonance Ltd., Shenzhen, China, 4Siemens Healthcare K.K., Tokyo, Japan

We evaluated the performance of diffusion MRI (dMRI) acquisition with simultaneous multi-slice (SMS) readout-segmented echo-planar imaging (rs-EPI) in measuring the uncinate fasciculus, which is typically affected by susceptibility-induced distortion or signal dropout. We found that SMS rs-EPI data provides a larger number of streamlines supported by dMRI data and larger fractional anisotropy in uncinate, as compared to conventional SMS single-shot EPI data. However, such an advantage was not consistent across subjects in the forceps major. Taken together, our results demonstrate that dMRI acquisition with SMS rs-EPI has advantages in measuring specific white matter tracts affected by susceptibility-induced artifacts.

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