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Abstract #4596

Investigating the change of optic radiation in Septo-optic dysplasia patients with DTI

Xiaoyu Wang1, Cong Tian1, Xinxin Tao1, Mengxuan Li1, Yuli Zhang1, Xiaocheng Wei2, and Jian Yang3
1The first affliated hospital of Xi'an Jiaotong University, Xi'an, China, 2MR Research China, GE Healthcare, Beijing, China, 3Radiology, The first affliated hospital of Xi'an Jiaotong University, Xi'an, China

Septo-optic dysplasia (SOD) is a rare congenital malformation disorder and have equally prevalent in males and females in early brain development. This study evaluated the micro-structure of optic radiation pathway using automatic fiber bundle quantization tracking (AFQ)in DT image to investigate the possible developmental impairment of optic radiation pathway that might cause by the abnormalanatomy structure of SOD patient. Result showed abnormal changes of optic radiation were found in SOD patients. The DTI tractography result could provides a non-invasive mapping of the optic radiation pathway and locate the injury.

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