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Abstract #4703

Replacing CT with high-resolution MRI for 3D pediatric cranial bone imaging

Kamlesh B. Patel1, Cihat Eldeniz2, Gary B. Skolnick3, Udayabhanu Jammalamadaka2, Paul K. Commean2, Manu S. Goyal2, Matthew D. Smyth4, and Hongyu An2
1Plastic and Reconstructive Surgery, Washington University in St. Louis, Saint Louis, MO, United States, 2Radiology, Washington University in St. Louis, Saint Louis, MO, United States, 3Surgery, Washington University in St. Louis, Saint Louis, MO, United States, 4Neurosurgery, Washington University in St. Louis, Saint Louis, MO, United States

Ionizing radiation from computed tomography (CT) imaging increases the risk of cancer. Patients with craniosynostosis often undergo repeated head CT scans, exacerbating the cumulative risk. Magnetic Resonance Imaging (MRI) has the potential to be a radiation-free safe alternative. Previously proposed methods in this area are not widely utilized because of suboptimal osseous/soft tissue contrast, vulnerability to motion, and the need for manual post-processing. In this study, we propose a high-resolution radial MRI protocol with improved tissue contrast and less sensitivity to motion. Moreover, we seek to evaluate its feasibility by using a blinded clinical evaluation.

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