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Abstract #4846

Prediction of Treatment Outcome after Radiosurgery in Brain Metastases from Lung Cancer Using Preradiosurgical MR Radiomics

Chien-Yi Liao1, Cheng-Chia Lee2,3,4, Huai-Che Yang2,3, Wen-Yuh Chung2,3, Hsiu-Mei Wu3,5, Wan-Yuo Guo3,5, Ren-Shyan Liu1,6, and Chia-Feng Lu1,7
1Department of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, Taipei, Taiwan, 2Department of Neurosurgery, Neurological Institute, Taipei Veteran General Hospital, Taipei, Taiwan, 3School of Medicine, National Yang-Ming University, Taipei, Taiwan, 4Brain Research Center, National Yang-Ming University, Taipei, Taiwan, 5Department of Radiology, Taipei Veteran General Hospital, Taipei, Taiwan, 6Department of Nuclear Medicine and National PET/Cyclotron Center, Taipei Veterans General Hospital, Taipei, Taiwan, 7Institute of Biophotonics, National Yang-Ming University, Taipei, Taiwan

The development of brain metastases is a devastating consequence of disease progression of advanced non-small cell lung cancer patients. This study proposed an approach to predict the treatment outcome after gamma knife radiosurgery based on preradiosurgical MR radiomics. We suggested that imaging characteristics extracted from preradiosurgical MRIs can be potential image biomarkers for the outcome prediction.

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