Abstract #0036

Value of Liver MR Elastography for Predicting Development of Cirrhosis and Decompensation in Patients with Alcohol-associated Liver Disease

Jingbiao Chen¹, Mahmoud Adam Tahboub Amawi², Xin Lu², Jie Chen³, Jiahui Li², Zheng Zhu², Safa Hoodeshenas², Jin Wang⁴, Douglas A Simonetto², Vijay H Shah², Richard L Ehman², and Meng Yin²

¹Radiology, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China, ²Mayo Clinic, Rochester, MN, United States, ³West China Hospital, Chengdu, China, ⁴the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China

Identifying those at high risk for the development of end-stage liver disease in patients with alcohol-associated liver disease (ALD) is of great clinical importance. We retrospectively investigated the role of MR elastography (MRE) in predicting cirrhosis or decompensated cirrhosis on a cohort of 182 ALD patients. Our preliminary results indicated that liver stiffness measured by 2D-MRE is a significant and independent prognostic factor for the future development of cirrhosis or decompensated cirrhosis. These results echoed the previous findings in other etiologies and reinforced the prognostic value of MRE in predicting advanced liver disease, which facilitates early intervention for ALD.

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