Abstract #0038

Highly Accelerated Wave-CAIPI 3D SPACE FLAIR Compared to Standard 3D SPACE FLAIR for Epilepsy Imaging at 3T

Augusto Lio M. Goncalves Filho^1,2, Chanon Ngamsombat³, Stephen F. Cauley², Wei Liu⁴, Daniel N. Splitthoff⁵, Wei-Ching Lo⁶, John E. Kirsch¹, Pamela W. Schaefer¹, Otto Rapalino¹, Susie Y. Huang^1,2, and John Conklin^1,2

¹Department of Radiology, Massachusetts General Hospital, Boston, MA, United States, ²Department of Radiology, Athinoula A. Martinos Center for Biomedical Imaging, Charlestown, MA, United States, ³Department of Radiology, Siriraj Hospital, Bangkok, Thailand, ⁴Siemens Shenzhen Magnetic Resonance Ltd., Shenzhen, China, ⁵Siemens Healthcare GmbH, Erlangen, Germany, ⁶Siemens Medical Solutions Inc., Boston, MA, United States

We performed a systematic comparison of highly accelerated Wave-CAIPI 3D SPACE FLAIR versus standard 3D SPACE FLAIR for the imaging evaluation of 77 patients with seizures or established epilepsy undergoing 3T MRI. There were no significant differences between the two sequences for the detection of lesions and overall diagnostic quality, despite a 2.5- to 4-fold decrease in acquisition time using Wave-CAIPI SPACE FLAIR. The application of highly accelerated 3D imaging using Wave-CAIPI technology may improve use of MRI resources while reducing motion artifacts and patient anxiety.

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