Meeting Banner
Abstract #0165

Myelin Water Fraction Mapping in developing children using Magnetic Resonance Fingerprinting

Matteo Cencini1,2, Marta Lancione2,3, Laura Biagi1,2, Jan W Kurzawski1,2, Rosa Pasquariello1, Graziella Donatelli2,4, Claudia Dosi1,5, Chiara Ticci1,5, Roberta Battini1,5, Guido Buonincontri1,2, and Michela Tosetti1,2
1IRCCS Stella Maris, Pisa, Italy, 2Imago7 Foundation, Pisa, Italy, 3IMT School for Advanced Studies Lucca, Lucca, Italy, 4Neuroradiology Unit, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy, 5Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy

Magnetic Resonance Fingerprinting (MRF) has been used to obtain Myelin Water Fraction (MWF) estimates in a cohort of developing children by using a three-component signal model. Here, we used a recent approach in which we perform sub-voxel tissue characterization without assumptions on the number and properties of the model components. We then used this signal model to study the myelination process in the developing brain on a 2D MRF dataset. Finally, we measured MWF on a set of subjects acquired with 3D MRF scan and compared the results to the 2D experiment.

This abstract and the presentation materials are available to members only; a login is required.

Join Here