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Abstract #0247

Susceptibility artifact correction in MR thermometry for monitoring of mild RF hyperthermia using total field inversion

Christof Boehm1, Marianne Goeger-Neff2, Hendrik T. Mulder3, Benjamin Zilles2, Lars H. Lindner2, Gerard C. van Rhoon3, Dimitrios C. Karampinos4, and Mingming Wu1
1Technical University of Munich, Munich, Germany, 2Department of Medicine III, University Hospital, LMU Munich, Munich, Germany, 3Erasmus MC Cancer Institute, Rotterdam, Netherlands, 4Department of Diagnostic and Interventional Radiology, School of Medicine, Technical University of Munich, Munich, Germany

Motion-induced susceptibility changes induce field variations, leading to large errors during MR thermometry based on the linear proton resonance frequency shift. These artefacts aggravate temperature quantification in the face of both the long treatment duration and the mild temperature change during mild RF hyperthermia treatments. We show with the help of simulations, a phantom heating experiment, volunteer scans and mild hyperthermia treatment of a patient with cervical cancer and a sarcoma patient how to correct for this artefact source by methods known from quantitative susceptibility mapping. The recently introduced total field inversion shows advantages over the background field removal methods.

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