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Abstract #0248

Fast MR thermometry based on propeller echo‐planar time‐resolved imaging with dynamic encoding (PEPTIDE)

Zhehong Zhang1, Fair Merlin2, Fuyixue Wang3,4, Zijing Dong3,5, Wending Tang1, Menghan Li1, Danna Wei6, Kawin Setsompop2,7, and Kui Ying1
1Department of Engineering Physics, Tsinghua University, Beijing, China, 2Department of Radiology, School of Medicine, Stanford University, Stanford, CA, United States, 3Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States, 4Harvard-MIT Health Sciences and Technology, MIT, Cambridge, MA, United States, 5Department of Electrical Engineering and Computer Science, MIT, Cambridge, MA, United States, 6Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China, 7Department of Electrical Engineering, Stanford University, Stanford, CA, United States

Echo‐planar time‐resolved imaging (EPTI) is a multi-shot EPI technique capable of rapidly obtaining distortion‐free and blurring‐free time-resolved multi-contrast images across the EPI readout. PROPELLER is an extension to EPTI, which incorporates PROPRELLER-like acquisition, to enable shot-to-shot motion toleration. In this work, PEPTIDE was applied to the MR thermometry application, where an image reconstruction framework that leveraged sparsity across blades of PEPTIDE rawdata was proposed. The potential in using PEPTIDE to provide distortion- and blurring-free temperature mapping at high temporal resolution was then demonstrated via simulated human brain PEPTIDE data with various temperature profiles.

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